Key Takeaways
- Understand the latest clinical recommendations for integrating NT-proBNP testing into routine T2DM care
- Discover insights from the multi-ethnic Asian PISCES study and how NT-proBNP performs in a real-world clinical setting
Introduction
The Asia-Pacific region is at the epicenter of the global diabetes epidemic, driving a parallel rise in cardiovascular disease (CVD). Heart failure (HF) is frequently the first CVD manifestation in individuals with Type 2 Diabetes (T2D).1 HF leads to deterioration in patients’ clinical course, marked by frequent hospitalizations and a gradual decline in their activities of daily living.2,3 People with T2D and HF have a 3-fold increased risk of death compared to those without HF.2,4 Despite this growing threat, early identification remains a critical challenge because many patients remain asymptomatic until advanced structural disease develops.
Join our expert-led educational webinar, “Taking Diabetes to Heart: The Value of NT-proBNP Testing for CVD Risk Assessment in Diabetes,” to explore the evolving role of NT-proBNP as a powerful tool for early CVD risk assessment. Our expert speakers will delve into the latest clinical guidelines and real-world evidence from the PISCES study involving multi-ethnic Asian populations, reviewing why traditional risk markers often fall short and how NT-proBNP testing is transforming early CVD risk stratification.
Faculty
Agenda
| Time (GMT+8) | Topic |
|---|---|
| 12:00 – 12:05 | Welcome & OpeningDr. Ameya Joshi |
| 12:05 – 12:25 | Guideline-Directed CVD Risk Assessment in Diabetes: The Role of NT-proBNPAssoc. Prof. Yuya Matsue |
| 12:25 – 12:50 | Rethinking CVD Risk Stratification in Asian T2D PatientsAssoc. Prof. Bee Yong Mong |
| 12:50 – 13:00 | Q&A and ClosingAll Faculty |
Dr. Bee is the Head and Senior Consultant of the Department of Endocrinology at Singapore General Hospital (SGH). He holds the position of Clinical Associate Professor at Duke-NUS Medical School, Singapore, and Director of the Data Science and Artificial Intelligence Laboratory (DSAIL) at SGH.
Dr. Bee graduated from the National University of Singapore (NUS) in 1998 and completed his specialist training in Endocrinology at SGH in 2007. He also received research training at the Joslin Diabetes Centre in Boston, USA, from 2009 to 2010 as a recipient of the Health Manpower Development Plan (HMDP) fellowship award.
His clinical focus is primarily on the management of diabetes mellitus and lipid disorders. Dr. Bee leads research programmes aimed at diabetes prevention, risk prediction for diabetic complications, and leveraging artificial intelligence in diabetes care. He was instrumental in establishing the SingHealth Diabetes Registry (SDR), a comprehensive multi-institutional database derived from the SingHealth Electronic Medical Record system.
In addition to his roles at SGH and SingHealth, Dr. Bee is the President of Diabetes Singapore (DS), the sole registered charitable organisation in Singapore devoted exclusively to the fight against diabetes.
References
- Shah AD, Langenberg C, Rapsomaniki E, Denaxas S, Pujades-Rodriguez M, Gale CP, Deanfield J, Smeeth L, Timmis A, Hemingway H. Type 2 diabetes and incidence of cardiovascular diseases: a cohort study in 1·9 million people. Lancet Diabetes Endocrinol. 2015 Feb;3(2):105-13. doi: 10.1016/S2213-8587(14)70219-0. Epub 2014 Nov 11.
- Cavender MA, Steg PG, Smith SC Jr, Eagle K, Ohman EM, Goto S, Kuder J, Im K, Wilson PW, Bhatt DL; REACH Registry Investigators. Impact of Diabetes Mellitus on Hospitalization for Heart Failure, Cardiovascular Events, and Death: Outcomes at 4 Years From the Reduction of Atherothrombosis for Continued Health (REACH) Registry. Circulation. 2015 Sep 8;132(10):923-31. doi: 10.1161/CIRCULATIONAHA.114.014796. Epub 2015 Jul 7.
- Olchanski N, Vest AR, Cohen JT, DeNofrio D. Comparing inpatient costs of heart failure admissions for patients with reduced and preserved ejection fraction with or without type 2 diabetes. Cardiovasc Endocrinol Metab. 2020 Feb 21;9(1):17-23. doi: 10.1097/XCE.0000000000000190.
- Gavina C, Carvalho DS, Dias DM, Bernardo F, Martinho H, Couceiro J, Santos-Araújo C, Dinis-Oliveira RJ, Taveira-Gomes T. Premature Mortality in Type 2 Diabetes Mellitus Associated with Heart Failure and Chronic Kidney Disease: 20 Years of Real-World Data. J Clin Med. 2022 Apr 11;11(8):2131. doi: 10.3390/jcm11082131.