{"id":4295,"date":"2020-10-30T19:59:59","date_gmt":"2020-10-30T11:59:59","guid":{"rendered":"https:\/\/cardiothinklab.com\/dapa-hf-%eb%b0%8f-emperor-reduced-%ec%9e%84%ec%83%81%ec%8b%9c%ed%97%98-%ed%95%98%ec%9d%b4%eb%9d%bc%ec%9d%b4%ed%8a%b8\/"},"modified":"2026-02-12T00:22:24","modified_gmt":"2026-02-11T16:22:24","slug":"dapa-hf-emperor-reduced-sglt2-insights","status":"publish","type":"post","link":"https:\/\/cardiothinklab.com\/ko\/dapa-hf-emperor-reduced-sglt2-insights\/","title":{"rendered":"DAPA-HF \ubc0f EMPEROR-Reduced \uc784\uc0c1\uc2dc\ud5d8 \ud558\uc774\ub77c\uc774\ud2b8"},"content":{"rendered":"\n

DAPA-HF\uc640 EMPEROR-Reduced\uc758 \uacb0\uacfc\uc5d0 \ub300\ud574 \uc5b4\ub5bb\uac8c \uc0dd\uac01\ud558\uc2ed\ub2c8\uae4c?<\/strong><\/h3>\n\n\n\n

EMPEROR-reduced\ub294 \ubc15\ucd9c\ub960(EF) \uac10\uc18c \uc2ec\ubd80\uc804 \ud658\uc790\ub4e4\uc744 \ub4f1\ub85d\ud588\uc2b5\ub2c8\ub2e4. \uc774\ub294 \ub300\uaddc\ubaa8 \uc784\uc0c1\uc2dc\ud5d8\uc73c\ub85c, 3700\uba85\uc774 \ub118\ub294 \ud658\uc790\ub4e4\uc774 \ub4f1\ub85d\ub418\uc5c8\uc73c\uba70, \ud658\uc790\ub4e4\uc740 \uc5e0\ud30c\uae00\ub9ac\ud50c\ub85c\uc9c4 10 \ubc00\ub9ac\uadf8\ub7a8 \ub610\ub294 \uc0c1\uc751\ud558\ub294 \uc704\uc57d\uc744 \ud22c\uc5ec \ubc1b\ub3c4\ub85d \ubb34\uc791\uc704 \ubc30\uc815\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

\uc9c0\ub09c \ud574 \ud30c\ub9ac\uc5d0\uc11c \uc5f4\ub9b0 ESC 2019\uc5d0\uc11c EMPEROR-reduced\uc640 \uac70\uc758 \uc720\uc0ac\ud558\ub098 \ub2e4\ud30c\uae00\ub9ac\ud50c\ub85c\uc9c4 10 \ubc00\ub9ac\uadf8\ub7a8\uc73c\ub85c \uc2e4\uc2dc\ud55c \uc784\uc0c1\uc2dc\ud5d8\uc778 DAPA-HF \uc784\uc0c1\uc2dc\ud5d8\uc758 \uacb0\uacfc\uac00 \ubc1c\ud45c\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc774 \uc784\uc0c1\uc2dc\ud5d8\uc740 \ub9e4\uc6b0 \ud601\uc2e0\uc801\uc778 \uacb0\uacfc\ub97c \ub3c4\ucd9c\ud558\uc600\uace0, \uc77c\ucc28 \ud3c9\uac00\ubcc0\uc218\uc778 \uc2ec\ubd80\uc804 \uc785\uc6d0\uacfc \uc2ec\ud608\uad00 \uc0ac\ub9dd, \ub610\ud55c \ub9ce\uc740 \uc774\ucc28 \ud3c9\uac00\ubcc0\uc218\uc758 \uac10\uc18c\uac00 \ub098\ud0c0\ub0a8\uc73c\ub85c\uc368, \ub9e4\uc6b0 \uc131\uacf5\uc801\uc778 \uc784\uc0c1\uc2dc\ud5d8\uc73c\ub85c \ud3c9\uac00\ub429\ub2c8\ub2e4.<\/p>\n\n\n\n

\ubaa8\ub450\uac00 EMPEROR-reduced\uc758 \uacb0\uacfc\ub97c \uac04\uc808\ud788 \uae30\ub2e4\ub838\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uacb0\uacfc\uac00 2\uac74\uc758 \uc784\uc0c1\uc2dc\ud5d8\uc5d0\uc11c \ud655\uc778\ub41c\ub2e4\uba74 \uacb0\uacfc\uc758 \uc2e0\ub8b0\uc131\uacfc \uc911\uc694\uc131\uc774 \ud6e8\uc52c \ub192\uc544\uc9c0\uae30 \ub54c\ubb38\uc785\ub2c8\ub2e4. EMPEROR-reduced\uac00 \uc815\ud655\ud788 \uc774\ub7ec\ud55c \uacb0\uacfc\ub97c \ud655\uc778\ud574 \uc8fc\uc5c8\uae30\uc5d0, \uc548\uc2ec\ud560 \uc218 \uc788\uc5c8\uc2b5\ub2c8\ub2e4. \uc77c\ucc28 \ud3c9\uac00\ubcc0\uc218\ub294 \uc774 \uc784\uc0c1\uc2dc\ud5d8\uc5d0\uc11c\ub3c4 \uc2ec\ubd80\uc804 \uc785\uc6d0 \ub610\ub294 \uc2ec\ud608\uad00 \uc0ac\ub9dd \uc911 \uba3c\uc800 \ubc1c\uc0dd\ud558\ub294 \uc0ac\uac74\uc774\uc5c8\uc73c\uba70, \uc774\ub294 \uc5e0\ud30c\uae00\ub9ac\ud50c\ub85c\uc9c4 \ud22c\uc5ec\ub85c \ud6a8\uacfc\uc801\uc73c\ub85c \uac10\uc18c\ud588\uae30\uc5d0(25%), \ud6a8\uacfc\uc758 \uc815\ub3c4\ub294 DAPA-HF\uc640 \uac70\uc758 100% \uc720\uc0ac\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

\n
\n

\n \ucd5c\uc2e0 \uc5c5\ub370\uc774\ud2b8 \uba54\uc77c \uc2e0\uccad\n <\/h3>\n \ucd5c\uc2e0 \uc815\ubcf4<\/a>\n <\/div>\n<\/div>\n\n\n\n
<\/div>\n\n\n\n

EMPEROR-reduced\uc5d0\ub294 3\uac1c\uc758 \uc0ac\uc804 \uc815\uc758\ub41c \uc77c\ucc28 \ud3c9\uac00\ubcc0\uc218\uac00 \uc788\uc5c8\uc73c\uba70, \uccab \ubc88\uc9f8\ub294 \uc2ec\ud608\uad00 \uc0ac\ub9dd\uacfc \uc2ec\ubd80\uc804 \uc785\uc6d0\uc774\uc5c8\uace0, \ub450 \ubc88\uc9f8\ub294 \ubc18\ubcf5\uc801\uc778 \uc2ec\ubd80\uc804 \uc785\uc6d0\uc774\uc5c8\uc73c\uba70, \uc138 \ubc88\uc9f8\ub294 \uc2e0\uc7a5 \ud3c9\uac00\ubcc0\uc218\uc600\uace0, \uc138 \uac00\uc9c0 \ud3c9\uac00\ubcc0\uc218 \ubaa8\ub450 \ucda9\uc871\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

\ub9ce\uc740 \uc774\ub4e4\uc774 \ubcf8\ub2a5\uc801\uc73c\ub85c EMPEROR-reduced\ub97c DAPA-HF\uc640 \ube44\uad50\ud574\uc57c \ud55c\ub2e4\uace0 \ub290\uaf08\uc73c\uba70, \uc800\ub294 \uc774 \ub450 \uc784\uc0c1\uc2dc\ud5d8 \uac04\uc5d0 \ucc28\uc774\uc810\ubcf4\ub2e4 \uc720\uc0ac\uc810\uc774 \ub354 \ub9ce\ub2e4\uace0 \uc0dd\uac01\ud569\ub2c8\ub2e4. \uac00\uc7a5 \uc911\uc694\ud55c \uc810\uc740 \uc77c\ucc28 \ud3c9\uac00\ubcc0\uc218\uc640 \uad00\ub828\ub41c \ud6a8\uacfc\uc758 \uc815\ub3c4\uac00 \uac70\uc758 \uc911\ubcf5\ub418\uc5c8\ub2e4\ub294 \uac83\uc774\uace0 \uc774\ub294 \uae0d\uc815\uc801\uc778 \uc810\uc785\ub2c8\ub2e4. \uba87 \uac00\uc9c0 \ucc28\uc774\uc810\uc774 \uc788\uc5c8\uc73c\uba70, \uc774 \uc911 \ub2e4\uc218\ub294 \uc784\uc0c1\uc2dc\ud5d8 \uc124\uacc4, \ud658\uc790 \uc120\uc815\uacfc \uad00\ub828\uc774 \uc788\ub2e4\uace0 \uc0dd\uac01\ud569\ub2c8\ub2e4. \ub530\ub77c\uc11c DAPA-HF\ub294 \ube44\uad50\uc801 \uc548\uc815\uc801\uc774\uace0 \uc9c8\ubcd1\uc774 \ub9ce\uc774 \uc9c4\ud589\ub418\uc9c0 \uc54a\uc740 \ud658\uc790\ub4e4\uc744 \ub4f1\ub85d\ud558\ub294 \uacbd\ud5a5\uc774 \uc788\uc5c8\ub358 \ubc18\uba74, EMPEROR-reduced\ub294 \ubcf4\ub2e4 \uc911\uc99d\uc758 \uc2ec\ubd80\uc804 \ud658\uc790\ub4e4\uc744 \ub354 \ub9ce\uc774 \ub4f1\ub85d\uc2dc\ucf30\uc73c\uba70, \uc774\ub294 EMPEROR-reduced\ub294 \ubc15\ucd9c\ub960\uc774 \ub9e4\uc6b0 \ub0ae\uc740(30% \uc774\ud558) \ud658\uc790\ub4e4\uc744 \ub4f1\ub85d\ud558\ub294 \ubcf5\uc7a1\ud55c \uc77c\uc815\uc744 \ub530\ub77c\uc57c \ud588\uae30 \ub54c\ubb38\uc774\uc5c8\uc2b5\ub2c8\ub2e4. \ubc15\ucd9c\ub960\uc774 30%\ub97c \ucd08\uacfc\ud558\uac70\ub098 35% \ubbf8\ub9cc\uc778 \uacbd\uc6b0, NT-proBNP\uc758 \uc120\uc815 \uae30\uc900\uc774 \ub2ec\ub790\uc73c\uba70, \uae30\uc900\uc774 \ud6e8\uc52c \ub354 \ub192\uc558\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc774\uc0c1\uc131 \uc784\uc0c1\uc2dc\ud5d8 \uc124\uacc4\ub85c \uc778\ud574, \uc2dc\ud5d8\uc790\ub4e4\uc740 DAPA-HF\uc5d0 \ucc38\uc5ec\ud55c \ud658\uc790\ub4e4\ubcf4\ub2e4 \ub354 \uc911\uc99d\uc758 \uc2ec\ubd80\uc804 \ud658\uc790\ub4e4\uc744 \ub4f1\ub85d\uc2dc\ucf1c\uc57c \ud588\uc73c\uba70, \uc774\ub7ec\ud55c \uc810\uc740 EMPEROR\uc758 \ud3c9\uade0 \ubc15\ucd9c\ub960\uc774 27%\uc600\ub358 \ubc18\uba74, DAPA-HF\uc5d0\uc11c\ub294 31%\uc600\uace0, EMPEROR\uc758 \ud3c9\uade0 NT-proBNP\uac00 1900\uc774\uc5c8\ub358 \ubc18\uba74, DAPA-HF\uc5d0\uc11c\ub294 1500\uc774\uc5c8\ub2e4\ub294 \uc0ac\uc2e4\ub85c \uc785\uc99d\ub429\ub2c8\ub2e4. \uc989 \uc774 \ub450 \uc2dc\ud5d8 \uac04\uc5d0\ub294 \uc57d\uac04\uc758 \ucc28\uc774\uac00 \uc788\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

\uacb0\uacfc\uc640 \uad00\ub828\ud558\uc5ec, \uc9c8\ubcd1 \uc911\uc99d\ub3c4\uc640 \uc77c\uce58\ud558\uac8c EMPEROR-reduced\uc5d0\uc11c 100 \ud658\uc790-\ub144\ub2f9 \ubcf4\ub2e4 \ub9ce\uc740 \uc77c\ucc28 \ud3c9\uac00\ubcc0\uc218\uac00 \ub098\ud0c0\ub0ac\uc73c\ub098, \uc774\ub294 \ub300\uccb4\uc801\uc73c\ub85c \ub192\uc740 \uc2ec\ubd80\uc804 \uc785\uc6d0\ub960 \ub54c\ubb38\uc774\uc5c8\uc2b5\ub2c8\ub2e4. \uc2ec\ud608\uad00 \uc0ac\ub9dd\ub960\uc740 \ub450 \uc784\uc0c1\uc2dc\ud5d8\ub4e4 \uac04\uc5d0 \uc720\uc0ac\ud588\uace0, \uadf8 \uacb0\uacfc EMPEROR\uc758 \uaddc\ubaa8\uac00 DAPA-HF\ubcf4\ub2e4 \ub354 \uc791\uc558\uae30\uc5d0(3700 \ub300 4700) \ud3c9\uade0 \ucd94\uc801\uad00\ucc30\ub3c4 \ub354 \uc9e7\uc558\uc2b5\ub2c8\ub2e4. EMPEROR\uc758 \ucd94\uc801 \uad00\ucc30 \uae30\uac04\uc740 16\uac1c\uc6d4\uc774\uc5c8\ub358 \ubc18\uba74 DAPA-HF\uc5d0\uc11c\ub294 18\uac1c\uc6d4\uc774\uc5c8\uc73c\uba70, \uc2ec\ud608\uad00 \uc0ac\ub9dd\uc5d0\uc11c \uc5e0\ud30c\uae00\ub9ac\ud50c\ub85c\uc9c4\uacfc \uc704\uc57d \uac04 \uc720\uc758\ud55c \ucc28\uc774\ub294 \uc5c6\uc5c8\uc2b5\ub2c8\ub2e4. \ub530\ub77c\uc11c \uc81c\uac00 \uc0dd\uac01\ud558\uae30\uc5d0 \uc774\ub294 \uac80\uc815\ub825 \ubd80\uc871 \ub54c\ubb38\uc774\uace0, \ub300\uc548 \uac00\uc124\uc740 \uc5e0\ud30c\uae00\ub9ac\ud50c\ub85c\uc9c4\uc774 \uc804\uccb4 \ud3c9\uac00\ubcc0\uc218\ub97c \uac10\uc18c\uc2dc\ud0a4\ub098 \uc2ec\ud608\uad00 \uc0ac\ub9dd\ub960\uc744 \uac10\uc18c\uc2dc\ud0a4\uc9c0 \uc54a\ub294\ub2e4\ub294 \uac83\uc785\ub2c8\ub2e4. \uc774\ub294 \uae30\uc804\uc801 \uad00\uc810\uacfc \ubcd1\ud0dc\uc0dd\ub9ac\ud559\uc801 \uad00\uc810\uc5d0\uc11c \uac00\ub2a5\uc131\uc774 \ub9e4\uc6b0 \ub0ae\uc740 \uc2dc\ub098\ub9ac\uc624\ub77c\uace0 \uc0dd\uac01\ud569\ub2c8\ub2e4. \ub450 \uc784\uc0c1\uc2dc\ud5d8\uc740 \uac01\uac01\uc758 \uacb0\uacfc\ub97c \uc11c\ub85c \uac15\ud654\ud55c\ub2e4\ub294 \uc810\uc744 \ub2e4\uc2dc \ud55c \ubc88 \uac15\uc870\ud569\ub2c8\ub2e4. \uc774\uc81c SGLT2 \uc5b5\uc81c\uac00 \ubc15\ucd9c\ub960 \uac10\uc18c \uc2ec\ubd80\uc804\uc5d0 \ub9e4\uc6b0 \uc720\uc775\ud558\ub2e4\ub294 \uacb0\uacfc\ub97c \uc815\ud655\ud558\uac8c \ubcf4\uc5ec\uc8fc\ub294 \uac80\uc815\ub825\uc774 \uc591\ud638\ud55c \ub300\uaddc\ubaa8 \uc784\uc0c1\uc2dc\ud5d8\uc774 1\uac74\uc5d0\uc11c 2\uac74\uc73c\ub85c \ub298\uc5b4\ub0ac\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

\uc800\ub294 \ub9e4\uc6b0 \uc911\uc694\ud55c \ub450 \uac00\uc9c0\uc758 \ucd94\uac00 \uad00\ucc30\uc0ac\ud56d\uc774 \uc788\ub2e4\uace0 \uc0dd\uac01\ud569\ub2c8\ub2e4. \uccab \ubc88\uc9f8\ub294 DAPA-HF\uc5d0\uc11c\uc640 \ub9c8\ucc2c\uac00\uc9c0\ub85c, EMPEROR-reduced\ub294 \uc81c2\ud615 \ub2f9\ub1e8\ubcd1\uc774 \uc788\uac70\ub098 \uc5c6\ub294 \ud658\uc790\ub4e4\uc744 \ub4f1\ub85d\uc2dc\ucf30\uace0, \uc57d\ubb3c\uc740 \ub2f9\ub1e8\ubcd1 \uc5ec\ubd80\uc640 \ubb34\uad00\ud558\uac8c \ub3d9\uc77c\ud558\uac8c \ud6a8\uacfc\uc801\uc774\uc5c8\ub2e4\ub294 \uac83\uc785\ub2c8\ub2e4. \ub530\ub77c\uc11c \ucc98\uc74c\uc5d0 \ub2f9\ub1e8\uc57d\uacfc \uac19\uc740 \uacbd\uad6c\uc6a9 \ud608\ub2f9\uac15\ud558\uc81c\ub85c \uc9c0\uc815\ub41c \uc774\ub7ec\ud55c \uc57d\ubb3c\ub4e4\uc740 \uc2e4\uc81c\ub85c \uadf8 \uc774\uc0c1\uc758 \ud6a8\uacfc\uac00 \uc788\uc73c\uba70, \uc774\ub4e4\uc740 \ub2f9\ub1e8\ubcd1 \uc0c1\ud0dc\uc640 \ubcc4\uac1c\ub85c \uc2ec\ubd80\uc804 \uc870\uc808 \uc57d\ubb3c\uc774\uae30\ub3c4 \ud558\ub2e4\ub294 \ucd94\uac00 \uc99d\uac70\ub4e4\uc774 \uc874\uc7ac\ud569\ub2c8\ub2e4. \uc7a5\uae30\uc801\uc73c\ub85c, \uc774 \uc57d\ubb3c\ub4e4\uc740 \ub2f9\ub1e8\ubcd1\uc774 \uc5c6\ub294 \uc2ec\ubd80\uc804 \ud658\uc790\ub4e4\uc5d0\uc11c \uc0ac\uc6a9\ub420 \uac83\uc73c\ub85c \uc608\uc0c1\ud560 \uc218 \uc788\uae30\uc5d0 \ub9e4\uc6b0 \uc911\uc694\ud569\ub2c8\ub2e4. \uc774\ub294 \ub9e4\uc6b0 \uc911\uc694\ud55c \uce21\uba74\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

\ub610 \ub2e4\ub978 \ub9e4\uc6b0 \uc911\uc694\ud55c \uce21\uba74\uc740 \uc801\uc6a9 \uac00\ub2a5\uc131\uacfc \uc548\uc804\uc131\uc785\ub2c8\ub2e4. \uc774\ub294 \uc6a9\uc774\ud55c \uc57d\ubb3c\uc785\ub2c8\ub2e4. \uc774 \ub450 \uc57d\ubb3c\uc758 \uc6a9\ub7c9\uc740 \uace0\uc815 \uc6a9\ub7c9\uc73c\ub85c, 10 \ubc00\ub9ac\uadf8\ub7a8\uc785\ub2c8\ub2e4. \ub3d9\uc77c\ud55c \uacc4\uc5f4 \ub0b4 \uc6a9\ub7c9\uc774 \ub2e4\ub978 \ub2e4\ub978 \uc57d\ubb3c\ub4e4\uc774 \uc788\uc73c\ub098, 10 \ubc00\ub9ac\uadf8\ub7a8\uc740 \uc989\uc2dc \ud22c\uc5ec\ub97c \uac1c\uc2dc\ud560 \uc218 \uc788\ub294 \uace0\uc815 \uc6a9\ub7c9\uc785\ub2c8\ub2e4. \uc801\uc815\ud560 \ud544\uc694\uac00 \uc5c6\uc73c\uba70 \uc774 \uc57d\ubb3c \uc0ac\uc6a9\uc5d0 \ub530\ub978 \ubd80\uc791\uc6a9\uc740 \ub9e4\uc6b0 \uc801\uc2b5\ub2c8\ub2e4. \ucde8\uc57d\ud55c \uc2ec\ubd80\uc804 \ud658\uc790\ub4e4\uc5d0\uc11c \ub9e4\uc6b0 \ud754\ud55c \ubd80\uc791\uc6a9\uc778 \uc2e0\uc7a5 \uae30\ub2a5\uc7a5\uc560\uc640 \uace0\ud608\uc555\uc740 \uc704\uc57d\uacfc \ube44\uad50\ud574 \ud65c\uc131 \uc57d\ubb3c\uc5d0 \ubc30\uc815\ub41c \ud658\uc790\ub4e4\uc5d0\uc11c \uc22b\uc790\uc801\uc73c\ub85c\ub098 \uc720\ubcd1\ub960 \uba74\uc5d0\uc11c \uc720\uc758\ud558\uac8c \ub354 \ub192\uc9c0 \uc54a\uc558\uc73c\uba70, \uc774\ub294 \ub9e4\uc6b0 \uc801\uc6a9 \uac00\ub2a5\ud558\uace0 \uc548\uc804\ud558\uba70 \uc548\uc2ec\ub418\ub294 \uacb0\uacfc\uc600\uc2b5\ub2c8\ub2e4. \ub2e4\uc2dc \ud55c \ubc88 \ub9d0\uc500\ub4dc\ub9ac\uba74, \uc774\ub294 ESC 2020\uc5d0\uc11c\uc758 \ud558\uc774\ub77c\uc774\ud2b8 \uc911 \ud558\ub098\uc600\uace0 \uc774 \uacb0\uacfc\ub294 \ub110\ub9ac \uc218\uc6a9\ub418\uace0 \ub17c\uc758\ub418\uc5c8\uc2b5\ub2c8\ub2e4. <\/p>\n\n\n\n

\uc774\ub7ec\ud55c \uacb0\uacfc\ub4e4\uc774 HFrEF \ud658\uc790\ub4e4\uc5d0\uc11c (ACEi\/ARBs\/ARNi, BB, MRA)\uc640 \ud568\uaed8 SGLT2 \uc5b5\uc81c\uc81c\ub97c \uc0c8\ub85c\uc6b4 \ud45c\uc900 \uce58\ub8cc\ub85c \ud655\ub9bd\ud558\uae30\uc5d0 \ucda9\ubd84\ud569\ub2c8\uae4c?<\/strong><\/h3>\n\n\n\n

 \uc774 \ubd84\uc57c\uc5d0\uc11c SGLT2 \uc5b5\uc81c\uc81c\uc758 \uc0ac\uc6a9\uc744 \uc815\ud655\ud788 \uacb0\uc815\ud558\ub294 \uac83\uc740 \uc5b4\ub824\uc6b8 \uac83\uc774\uc9c0\ub9cc, \uc774\uc81c \uc774 2\uac74\uc758 \uc784\uc0c1\uc2dc\ud5d8\uc774 \uc788\uae30\uc5d0, \uc77c\uc815 \ud615\ud0dc\uc758 \uad8c\uace0\uc0ac\ud56d\uc774 \ub098\uc62c \uac83\uc774\ub77c\ub294 \ub370\uc5d0\ub294 \uc758\uc2ec\uc758 \uc5ec\uc9c0\uac00 \uc5c6\ub2e4\uace0 \uc0dd\uac01\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n

\uc81c\uac8c \ud765\ubbf8\ub85c\uc6b4 \uc810\uc740 \uc2ec\ubd80\uc804\uc774 \ubc1c\uc0dd\ud558\ub294 \ub300\ubd80\ubd84\uc758 \ud658\uc790\ub4e4\uc5d0\uac8c \ube44\ub9cc, \ub2f9\ub1e8\ubcd1, \uace0\ud608\uc555\uacfc \uac19\uc740 \uc5ec\ub7ec \uc720\ubc1c \uc694\uc778\ub4e4\uc774 \uc874\uc7ac\ud560 \uac83\uc774\ub77c\ub294 \uc810\uc785\ub2c8\ub2e4. \ub2e4\uc2dc \ub9d0\ud574, \uc774\ub4e4\uc740 \uc2ec\ud608\uad00 \uc704\ud5d8\uc774 \ub192\uc73c\uba70 \ud604\ud589 \ub2f9\ub1e8\ubcd1 \uc9c0\uce68\uc5d0 \ub530\ub77c \ub9ce\uc740 \ud658\uc790\ub4e4\uc774 \uc2ec\ubd80\uc804 \ubc1c\uc0dd \uc804 \uc774\ubbf8 SGLT2 \uc5b5\uc81c\uc81c\ub97c \ud544\uc694\ub85c \ud560 \uac83\uc785\ub2c8\ub2e4. \ub530\ub77c\uc11c \uc5b4\ub290 \uc815\ub3c4\ub294, \uc774\ub7ec\ud55c \uc57d\ubb3c\uc744 \uc5b4\ub514\uc11c, \uc5b8\uc81c, \uc5b4\ub5bb\uac8c \uc2dc\uc791\ud574\uc57c \ud560\uc9c0\uc5d0 \ub300\ud55c \uc774\ub7ec\ud55c \ub51c\ub808\ub9c8\ub294 \uc2ec\ubd80\uc804 \uc758\uc0ac\uc5d0\uac8c\ub294 \ud574\ub2f9\ub418\uc9c0 \uc54a\uc744 \uac83\uc774\ub098, \ub2e4\ub978 \uc758\uc0ac\ub4e4\uc5d0\uac8c\ub294 \uc774\ub7ec\ud55c \uc57d\ubb3c\uc774 \ud544\uc694\ud55c \uacbd\uc6b0\ub97c \uc815\ud655\ud788 \ud310\ub2e8\ud558\ub294 \uac83\uc774 \ub51c\ub808\ub9c8\uc77c \uac83\uc785\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uc544\uc9c1 SGLT2 \uc5b5\uc81c\uc81c\ub85c \uce58\ub8cc\ubc1b\uc9c0 \uc54a\ub294 \uc2e0\uaddc \ubc1c\ubcd1 \uc2ec\ubd80\uc804 \ud658\uc790\ub97c \uc0dd\uac01\ud55c\ub2e4\uba74, \ub2f9\uc5f0\ud788 \uac00\uc6a9\ud55c \ub370\uc774\ud130\ub97c \uac80\ud1a0\ud574\uc57c \ud569\ub2c8\ub2e4. \ub2e4\uc2dc \ud55c \ubc88, DAPA-HF\uc640 EMPEROR-reduced\uc758 \ub450 \uc784\uc0c1\uc2dc\ud5d8\uc5d0\uc11c \ud658\uc790\ub4e4\uc740 \uc774\ubbf8 \ub9e4\uc6b0 \uc0c1\ub2f9\ud55c \ubc30\uacbd \uc694\ubc95\uc744 \ud22c\uc5ec\ubc1b\uc558\uace0 \uc5ec\uc804\ud788 \uc99d\uc0c1\uc131\uc774\uace0 \uc5ec\uc804\ud788 \ubc15\ucd9c\ub960\uc774 \uac10\uc18c\ud55c \uc0c1\ud0dc\uc600\uc73c\uba70, \uc774 \uc57d\ubb3c\ub4e4\uc5d0 \ubb34\uc791\uc704 \ubc30\uc815\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc2ec\ubd80\uc804 \uc9c0\uce68\uc758 \uad8c\uc7a5\uc0ac\ud56d\uc774 \uc784\uc0c1\uc2dc\ud5d8 \uc124\uacc4\ub97c \ub530\ub97c \uac00\ub2a5\uc131\uc774 \ub9e4\uc6b0 \ub192\ub2e4\uace0 \uc0dd\uac01\ud569\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \ub2e4\uc2dc \ub9d0\uc500\ub4dc\ub9ac\uc9c0\ub9cc \uc774\uc81c \uc774 \uc57d\ubb3c\ub4e4\uc774 \ub2f9\ub1e8\ubcd1\uc5d0\uc11c 1\ucc28 \uce58\ub8cc\uc81c\ub85c \uc120\ud0dd\ub418\uae30\uc5d0 \uc774 \uc57d\ubb3c\ub4e4\uc744 \ud22c\uc5ec\ubc1b\uac8c \ub420 \ud658\uc790 \uc218\uac00 \ud6e8\uc52c \ub354 \ub9ce\uc744 \uac00\ub2a5\uc131\uc774 \uc788\uc73c\uba70, \ub2f9\ub1e8\ubcd1\uacfc \uc2ec\ud608\uad00 \uc704\ud5d8 \uad00\ub9ac \uc9c0\uce68\uc5d0\uc11c \uc774\ub7ec\ud55c \uc57d\ubb3c\ub4e4\uc774 \ub110\ub9ac \uad8c\uc7a5\ub420 \uac83\uc73c\ub85c \uc0dd\uac01\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n

\uc2ec\ubd80\uc804\uacfc \ub9cc\uc131 \uc2e0\uc9c8\ud658 \ud658\uc790\ub4e4\uc5d0\uc11c SGLT2 \uc5b5\uc81c\uc81c\uc758 \uc5ed\ud560\uc740 \ubb34\uc5c7\uc785\ub2c8\uae4c?<\/strong><\/h3>\n\n\n\n

\uc774 \uc57d\ubb3c\ub4e4\uc740 \uc774\ubbf8 \uc81c2\ud615 \ub2f9\ub1e8\ubcd1 \uc784\uc0c1\uc2dc\ud5d8 EMPA-REG, CANVAS \ud504\ub85c\uadf8\ub7a8, DECLARE-TIMI\uc5d0\uc11c \uad00\ucc30\ub41c \uc2e0\uc7a5 \ubcf4\ud638 \ud6a8\uacfc\ub85c \uc778\ud574 \uc2e0\uc7a5\uc804\ubb38\uc758\uc640 \uc2e0\uc7a5 \uc9c8\ud658\uc5d0 \uad00\uc2ec\uc774 \uc788\ub294 \ub0b4\uacfc\uc758\ub4e4\uc758 \ub9ce\uc740 \uad00\uc2ec\uc744 \ubc1b\uc558\uc2b5\ub2c8\ub2e4. \ub610\ud55c ESC 2020\uc5d0\uc11c, \ub610 \ub2e4\ub978 \uc911\uc694\ud55c \uc784\uc0c1\uc2dc\ud5d8\uc778 DAPA-CKD \uc784\uc0c1\uc2dc\ud5d8\uc774 \ubc1c\ud45c\ub418\uc5c8\uc73c\uba70, \uc774\ub294 \uc2e0\uc7a5\uacfc \uc2ec\ud608\uad00 \ud3c9\uac00\ubcc0\uc218 \uc218\ub97c \uc904\uc774\uae30 \uc704\ud55c \ub178\ub825\uc758 \uc77c\ud658\uc73c\ub85c \uc2e0\uc7a5\ubcd1\uc99d \ud658\uc790\ub4e4\uc5d0\uac8c \ub2e4\ud30c\uae00\ub9ac\ud50c\ub85c\uc9c4\uc744 \ud22c\uc5ec\ud55c \uc784\uc0c1\uc2dc\ud5d8\uc774\uc5c8\uc2b5\ub2c8\ub2e4. \uc774 \uc784\uc0c1\uc2dc\ud5d8\uc758 \uacb0\uacfc \uc5ed\uc2dc \uc555\ub3c4\uc801\uc73c\ub85c \uae0d\uc815\uc801\uc774\uc5c8\uc73c\uba70 \uc774\ubc88 \uc8fc \ub274\uc789\uae00\ub79c\ub4dc \uc758\ud559 \uc800\ub110(New England Journal of Medicine)\uc5d0 \ubc1c\ud45c\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc774\ub294 \ub9e4\uc6b0 \uc911\uc694\ud55c \uc784\uc0c1\uc2dc\ud5d8\uc774\ub77c\uace0 \uc0dd\uac01\ud569\ub2c8\ub2e4. \uc800\ub294 \uc2e0\uc7a5\uc804\ubb38\uc758\uac00 \uc544\ub2c8\uc9c0\ub9cc, \uc6b0\ub9ac\ub294 \uc2e0\uc7a5\ubcd1\uc99d \ud658\uc790\ub4e4\uc5d0\uc11c eGFR \uac10\uc18c\ub97c \uc644\ud654\uc2dc\ud0a4\ub294 \uac83\uc774 \uc5bc\ub9c8\ub098 \uc5b4\ub824\uc6b4\uc9c0, \ub2e8\ubc31\ub1e8\ub97c \uc81c\ud55c\ud558\ub294 \uac83\uc774 \uc5bc\ub9c8\ub098 \uc5b4\ub824\uc6b4\uc9c0 \uc54c\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub294 \uc815\ud655\ud788 DAPA-CKD\uc758 \uc784\uc0c1\uc2dc\ud5d8 \ubaa8\uc9d1\ub2e8\uc73c\ub85c, \ub2e4\uc2dc \ud55c \ubc88 SGLT2 \uc5b5\uc81c\uc81c\uac00 \uc774 \ubaa8\uc9d1\ub2e8\uc5d0\uc11c\ub3c4 \ub9e4\uc6b0 \ud6a8\uacfc\uc801\uc778 \uac83\uc73c\ub85c \uc785\uc99d\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

\uc774\uc81c \uce74\ub098\uae00\ub9ac\ud50c\ub85c\uc9c4\uc744 \uc0ac\uc6a9\ud55c CREDENCE \uc784\uc0c1\uc2dc\ud5d8\uc744 \ud1b5\ud574 SGLT2 \uc5b5\uc81c\uc81c\uac00 \uc2e0\uc7a5 \ubcf4\ud638\uc131\uc774\uba70, \uc774 \uc57d\ubb3c\uc774 \uc2ec\ubd80\uc804 \uce58\ub8cc\uc5d0 \uc911\uc694\ud558\ub2e4\ub294 \uac15\uac74\ud55c \uc99d\uac70\ub4e4\uc774 \uc874\uc7ac\ud55c\ub2e4\uace0 \uc0dd\uac01\ud569\ub2c8\ub2e4. \ub9ce\uc740 \uce58\ub8cc\uac00 \uc2e4\uc81c\ub85c \uc2e0\uc7a5 \ubd80\uc791\uc6a9\uc73c\ub85c \uc778\ud574 \uc81c\ud55c\ub428\uc5d0\ub3c4 \uc2ec\ubd80\uc804 \ubd84\uc57c\ub294 \uc774\uc81c \uc2ec\ubd80\uc804\uc5d0\uc11c SGLT2 \uc5b5\uc81c\uc81c\ub97c \uc0ac\uc6a9\ud568\uc73c\ub85c\uc368 \ub354 \uc774\uc0c1 \uc2e0\uc7a5 \ubd80\uc791\uc6a9\uc744 \ub450\ub824\uc6cc\ud560 \ud544\uc694\uac00 \uc5c6\ub2e4\ub294 \uac83\uc744 \uc54c\uae30 \ub54c\ubb38\uc785\ub2c8\ub2e4. \ubc18\ub300\ub85c, \uc2e0\uc7a5 \ubcf4\ud638 \ud6a8\uacfc\ub97c \uae30\ub300\ud560 \uc218 \uc788\uc744 \uac83\uc73c\ub85c \uc0dd\uac01\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n

DAPA-HF\uc640 EMPEROR-reduced\uc5d0\uc11c, \uc2e4\uc81c\ub85c eGFR \uac10\uc18c \ub454\ud654\uac00 \uc788\uc5c8\uae30\uc5d0 \uc2e0\uc7a5 \ubcf4\ud638 \ud6a8\uacfc\uac00 \uc2e4\uc81c\ub85c \uc7ac\ud604\ub418\uc5c8\uc2b5\ub2c8\ub2e4. DAPA-HF\uc5d0\uc11c eGFR\uc758 \ubcf4\ub2e4 \ub0ae\uc740 \uc81c\uc678 \uae30\uc900\uc740 30\uc774\uc5c8\uc73c\ub098 EMPEROR-reduced\uc5d0\uc11c\ub294 20\uc5d0 \ubd88\uacfc\ud588\uc2b5\ub2c8\ub2e4. \ub530\ub77c\uc11c \uc774\uc81c \uc2ec\ubd80\uc804\uc758 eGFR \ubc94\uc704\uc5d0\uc11c \uc774 \uc57d\ubb3c\ub4e4\uc774 \uc720\uc775\ud558\uace0 \uc548\uc804\ud558\uba70 \uc544\ub9c8\ub3c4 \uc2e0\uc7a5 \ubcf4\ud638 \ud6a8\uacfc\uac00 \uc788\uc744 \uac83\uc774\ub77c\ub294 \uc124\ub4dd\ub825 \uc788\ub294 \uc99d\uac70\ub4e4\uc774 \uc788\ub2e4\uace0 \uc0dd\uac01\ud569\ub2c8\ub2e4. \uc774\ub294 \ub9e4\uc6b0 \uc911\uc694\ud55c \uce21\uba74\uc73c\ub85c\uc11c \uc758\uc0ac\ub4e4\uc774 \ubc14\ub77c\ub294 \uc720\ud6a8\uc131\uacfc \uc548\uc804\uc131\uc785\ub2c8\ub2e4.<\/p>\n","protected":false},"excerpt":{"rendered":"

DAPA-HF\uc640 EMPEROR-Reduced\uc758 \uacb0\uacfc\uc5d0 \ub300\ud574 \uc5b4\ub5bb\uac8c \uc0dd\uac01\ud558\uc2ed\ub2c8\uae4c? EMPEROR-reduced\ub294 \ubc15\ucd9c\ub960(EF) \uac10\uc18c \uc2ec\ubd80\uc804 \ud658\uc790\ub4e4\uc744 \ub4f1\ub85d\ud588\uc2b5\ub2c8\ub2e4. \uc774\ub294 \ub300\uaddc\ubaa8 \uc784\uc0c1\uc2dc\ud5d8\uc73c\ub85c, 3700\uba85\uc774 \ub118\ub294 \ud658\uc790\ub4e4\uc774 \ub4f1\ub85d\ub418\uc5c8\uc73c\uba70, \ud658\uc790\ub4e4\uc740 \uc5e0\ud30c\uae00\ub9ac\ud50c\ub85c\uc9c4 10 \ubc00\ub9ac\uadf8\ub7a8 \ub610\ub294 \uc0c1\uc751\ud558\ub294 \uc704\uc57d\uc744 \ud22c\uc5ec \ubc1b\ub3c4\ub85d \ubb34\uc791\uc704 \ubc30\uc815\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc9c0\ub09c \ud574 \ud30c\ub9ac\uc5d0\uc11c \uc5f4\ub9b0 ESC 2019\uc5d0\uc11c EMPEROR-reduced\uc640 \uac70\uc758 \uc720\uc0ac\ud558\ub098 \ub2e4\ud30c\uae00\ub9ac\ud50c\ub85c\uc9c4 10 \ubc00\ub9ac\uadf8\ub7a8\uc73c\ub85c \uc2e4\uc2dc\ud55c \uc784\uc0c1\uc2dc\ud5d8\uc778 DAPA-HF \uc784\uc0c1\uc2dc\ud5d8\uc758 \uacb0\uacfc\uac00 \ubc1c\ud45c\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc774 \uc784\uc0c1\uc2dc\ud5d8\uc740 \ub9e4\uc6b0 \ud601\uc2e0\uc801\uc778 \uacb0\uacfc\ub97c \ub3c4\ucd9c\ud558\uc600\uace0, \uc77c\ucc28 […]<\/p>\n

\ub354\ubcf4\uae30…<\/a><\/p>\n","protected":false},"author":3,"featured_media":2851,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[310,410],"tags":[],"specialty":[695],"class_list":["post-4295","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-latest-perspectives","category-esc-2020","specialty-cardiovascular-ko"],"acf":[],"_links":{"self":[{"href":"https:\/\/cardiothinklab.com\/ko\/wp-json\/wp\/v2\/posts\/4295","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cardiothinklab.com\/ko\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cardiothinklab.com\/ko\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cardiothinklab.com\/ko\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/cardiothinklab.com\/ko\/wp-json\/wp\/v2\/comments?post=4295"}],"version-history":[{"count":4,"href":"https:\/\/cardiothinklab.com\/ko\/wp-json\/wp\/v2\/posts\/4295\/revisions"}],"predecessor-version":[{"id":9166,"href":"https:\/\/cardiothinklab.com\/ko\/wp-json\/wp\/v2\/posts\/4295\/revisions\/9166"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cardiothinklab.com\/ko\/wp-json\/wp\/v2\/media\/2851"}],"wp:attachment":[{"href":"https:\/\/cardiothinklab.com\/ko\/wp-json\/wp\/v2\/media?parent=4295"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cardiothinklab.com\/ko\/wp-json\/wp\/v2\/categories?post=4295"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cardiothinklab.com\/ko\/wp-json\/wp\/v2\/tags?post=4295"},{"taxonomy":"specialty","embeddable":true,"href":"https:\/\/cardiothinklab.com\/ko\/wp-json\/wp\/v2\/specialty?post=4295"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}